发明名称 Vanadium (IV) metallocene complexes having sperm motility inhibiting activity
摘要 Novel spermicidal compounds which are organometallic cyclopentadienyl metal complexes, particularly vanadium IV complexes, are described including corresponding contraceptive and therapeutic compositions and method for providing contraception and selective killing of testicular germ cells. Included among the vanadium complexes are vanadocene dichloride, vanadocene dibromide, bis (methyl cyclopentadienyl) vanadium dichloride, vanadocene diiodide, vanadocene di-pseudohalides, and others. Most active found was vanadocene diselenocyanate.
申请公布号 US6051603(A) 申请公布日期 2000.04.18
申请号 US19980008898 申请日期 1998.01.20
申请人 WAYNE HUGHES INSTITUTE 发明人 D'CRUZ, OSMOND;GHOSH, PHALGUNI;UCKUN, FATIH M.
分类号 A61P15/16;A61K31/28;A61K31/555;A61P35/00;C07F17/00;(IPC1-7):A61K31/28 主分类号 A61P15/16
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