发明名称 ANTISENSE MODULATION OF INTEGRIN alpha 4 EXPRESSION
摘要 Compositions and methods are provided for modulating the expression of integrin alpha 4. Antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding integrin alpha 4 are preferred. Methods of using these compounds for modulating integrin alpha 4 expression and for treatment of diseases associated with expression of integrin alpha 4 are also provided.
申请公布号 WO0020635(A1) 申请公布日期 2000.04.13
申请号 WO1999US18796 申请日期 1999.08.19
申请人 ISIS PHARMACEUTICALS, INC.;BENNETT, C., FRANK;CONDON, THOMAS, P.;COWSERT, LEX, M. 发明人 BENNETT, C., FRANK;CONDON, THOMAS, P.;COWSERT, LEX, M.
分类号 C12N15/09;A61K31/7115;A61K31/712;A61K31/7125;A61K38/00;A61K48/00;A61P1/00;A61P1/16;A61P3/00;A61P11/06;A61P25/28;A61P29/00;A61P35/00;A61P35/04;A61P37/06;A61P43/00;C07H21/04;C12N15/113;C12Q1/02;C12Q1/68;(IPC1-7):C12Q1/68;C12N15/00;C12N15/85 主分类号 C12N15/09
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