PHOTOSENSITIZERS FOR PHOTODYNAMIC APPLICATIONS

摘要

A family of benzochlorin derivatives of formulas of Figs. 1A and 1B of the attached drawing are suitable for use as photosensitizers in photodynamic therapy. Solutions of the benzochlorin derivatives are physiologically accepted for selective destruction of cells and tissues. A method of destroying cells and tissues through a photodynamic process wherein a pharmaceutical composition including the benzochlorin derivates of formulas of Figs, 1A and 1B are administered to a human or anim al patient and light sufficient to generate a cytotoxic effect is supplied.