摘要 |
<p>Novel glutathione reductase activity intensifiers, which are compounds having general formula (I) and pharmacologically acceptable salts, thioesters, and other derivatives thereof, wherein m is 0 or 1; n is 2 when m is 0, and n is 1 when m is 1; k is an integer of 0 to 12; R1 is hydrogen, one member selected from substituents α, etc.; A is a group having -N(R2)CO-, -CON(R2)CO-, or -CON(R2)SO2- (R2 is hydrogen, alkyl, etc.), etc; and B is a single bond, -N(R5)- (R5 is hydrogen, alkyl, etc.), etc. [Substituents α] optionally substituted aryls, optionally substituted heterocyclic groups [Substituents β] alkyls, halogenated lower alkyls, etc. [Substituents η] lower alkoxys, hydroxy, etc.</p> |