| 摘要 |
<p>Bis-benzimidazole compounds of general formula (I) in which R?1, R2, R3 and R4¿ are hydrogen, hydroxy or halogen, R?5 and R8¿ are hydrogen, or (C¿1?-C4)-alkyl,R?6 and R7¿ are hydrogen, or (C¿1?-C6)-alkyl, hydroxy, halogen, or (C1-C6)-alkoxy, R?9, R10 and R11¿ are hydrogen, halogen, nitro, cyano or trifluoromethyl, and A is a non-aromatic 5-7-membered N-heterocycle, etc, process for their preparation and their use for treating diseases associated with tryptase activity including allergic, inflammatory and related immunological diseases, in particular asthma, allergic rhinitis, allergic conjunctivitis and allergic dermatitis.</p> |
