摘要 |
Remedies for motor dysfunction and GAPDH expression inhibitors containing as the active ingredient N-[3-[N-(4-chlorophenylmethyl)-carbamoyl]propanoyl]-L-prolinal. Because of having an effect of ameliorating motor dysfunction, N-[3-[N-(4-chlorophenylmethyl)-carbamoyl]propanoyl]-L-prolinal is useful in treating motor dysfunction caused by trauma, infection, degeneration, ischemia, tumor, etc. Also, it is useful in treating diseases caused by apoptosis in the cerebellum, spinal nerve nucleus or conduction route due to the overexpression of GAPDH (Parkinson's disease, Parkinson's syndrome, Huntington's disease, MJD, ALS, CHJ, etc.).
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