发明名称 REMEDIES FOR MOTOR DYSFUNCTION AND GAPDH EXPRESSION INHIBITORS
摘要 Remedies for motor dysfunction and GAPDH expression inhibitors containing as the active ingredient N-[3-[N-(4-chlorophenylmethyl)-carbamoyl]propanoyl]-L-prolinal. Because of having an effect of ameliorating motor dysfunction, N-[3-[N-(4-chlorophenylmethyl)-carbamoyl]propanoyl]-L-prolinal is useful in treating motor dysfunction caused by trauma, infection, degeneration, ischemia, tumor, etc. Also, it is useful in treating diseases caused by apoptosis in the cerebellum, spinal nerve nucleus or conduction route due to the overexpression of GAPDH (Parkinson's disease, Parkinson's syndrome, Huntington's disease, MJD, ALS, CHJ, etc.).
申请公布号 WO0020387(A1) 申请公布日期 2000.04.13
申请号 WO1999JP05414 申请日期 1999.10.01
申请人 ONO PHARMACEUTICAL CO., LTD.;ISHITANI, RYOICHI;KATSUBE, NOBUO 发明人 ISHITANI, RYOICHI;KATSUBE, NOBUO
分类号 A61K31/40;A61K31/401;(IPC1-7):C07D207/08 主分类号 A61K31/40
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