发明名称 |
NUCLEIC ACID ENCODING HYALURONAN SYNTHASE AND METHODS OF USE |
摘要 |
The present invention relates to a nucleic acid segment having a coding region segment encoding enzymatically active bacterial multocida hyaluronate synthase (PmHAS), and to the use of this nucleic acid segment in the preparation of recombinant cells which produce hyaluronate synthase and its hyaluronic acid product. Hyaluronate is also known as hyaluronic acid or hyaluronan. The present invention also relates to the use of the PmHAS in constructing "knock-out" mutant strains of P. multocida for use in vaccinations. The present invention further relates to the use of the PmHAS in diagnostic tests in the field determinations of livestock P. multocida infection. |
申请公布号 |
WO9951265(A9) |
申请公布日期 |
2000.04.13 |
申请号 |
WO1999US07289 |
申请日期 |
1999.04.01 |
申请人 |
BOARD OF REGENTS OF THE UNIVERSTIY OF OKLAHOMA |
发明人 |
DEANGELIS, PAUL |
分类号 |
G01N33/48;A61K39/00;A61K39/102;A61K47/36;A61P31/04;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N9/00;C12N9/10;C12N15/09;C12P19/04;C12Q1/02;C12Q1/68;G01N33/53;G01N33/566 |
主分类号 |
G01N33/48 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|