发明名称 |
COMPOSITIONS AND METHODS OF DISEASE DIAGNOSIS AND THERAPY |
摘要 |
The invention pertains to isolated nucleic acid molecules containing sequences specified herein, to mutant CD36 genes and their encoded gene products, to methods of screening blood or a blood product by detecting a CD36 gene mutation, methods of administering blood or a blood product based on the presence or absence of a CD36 gene mutation, to methods of matching a biological sample donor with a recipient based on detection of a mutation in the CD36 gene, methods of determining the resistance of a patient to infection by a parasite by detecting a CD36 gene mutation, methods of diagnosing a disease associated with a defect in insulin action, glucose metabolism, fatty acid metabolism, and/or catecholamine action by detecting a mutation in the CD36 gene, and methods of disease treatment by altering the mutation(s).
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申请公布号 |
WO0019883(A2) |
申请公布日期 |
2000.04.13 |
申请号 |
WO1999US23418 |
申请日期 |
1999.10.07 |
申请人 |
MEDICAL RESEARCH COUNCIL;SCIOS INC.;AITMAN, TIMOTHY, J.;SCOTT, JAMES;STANTON, LAWRENCE, W. |
发明人 |
AITMAN, TIMOTHY, J.;SCOTT, JAMES;STANTON, LAWRENCE, W. |
分类号 |
G01N33/50;A61K31/713;A61K38/00;A61K45/00;A61K48/00;A61P3/06;A61P3/10;A61P9/00;A61P9/12;A61P33/06;C07K14/47;C07K14/705;C12N15/09;C12Q1/68;G01N33/15;(IPC1-7):A61B/ |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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