| 摘要 |
There is described a formulation comprising a foamable gelling agent (such a s alginate, carageenan or carboxymethylcellulose gels) and a slow-release precipitant therefor. The precipitant is combined with th e gelling agent during foaming and stabilises the foamed form of the gelling agent. Suitable precipitants include calcium salts such as calcium citrate and calcium chloride, or aluminium salts such as aluminium chloride. The increased stability of the foam facilitates sterilisation thereof. Further improvements can be obtained by exposing the cured foam to a precipitant applied externally, optionally washing, and then drying the foam. The foam of the present invention is suitable for medical or veterinary use and can include active ingredients fo r delivery to, for example, a wound site.
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