| 发明名称 |
ZINC FINGER PEPTIDE CLEAVAGE OF NUCLEIC ACIDS |
| 摘要 |
Selective cleavage of single stranded nucleic acids can be effected by contacting the nucleic acid with a zinc finger peptide in dimeric form. Dimerization results from diminution or elimination of zinc from the peptide, such that easily controllable and highly selective cleavage may be realized.
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| 申请公布号 |
WO0020622(A1) |
申请公布日期 |
2000.04.13 |
| 申请号 |
WO1999US23273 |
申请日期 |
1999.10.06 |
| 申请人 |
ISIS PHARMACEUTICALS, INC. |
发明人 |
LIMA, WALT, F.;CROOKE, STANLEY, T.;MANOHARAN, MUTHIAH |
| 分类号 |
C12N15/09;C07K14/47;C12N9/16;C12N9/22;C12N15/10;(IPC1-7):C12P21/06;C12N5/00;C12N1/00;C12N15/00;C07K1/00;C07H21/04 |
主分类号 |
C12N15/09 |
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