MEDICINAL COMPOSITIONS AGAINST HELICOBACTER PYLORI

摘要

An anti-Helicobacter pylori pharmaceutical composition containing a 1-hydroxy-3-methyl-quinolone derivative represented by the following formula (I) <CHEM> or a pharmaceutically acceptable salt thereof as an active ingredient. Since it shows antibacterial action upon Helicobacter pylori, this invention is effective for the treatment or prevention of infection with Helicobacter pylori in human and infection with related bacteria belonging to the genus Helicobacter in animals. Also, the anti-Helicobacter pylori pharmaceutical composition of the present invention is useful for the prevention (including prevention of relapse) or treatment of diseases of the upper digestive organs, such as peptic ulcers (e.g., gastric and duodenal ulcers), inflammations (e.g., acute or chronic gastritis or duodenitis) and gastric cancer, as well as MALT (mucosa-associated lymphoid tissue) lymphoma or chronic heart diseases.