发明名称 Use of pregnane-diones as analgesic agents
摘要 The present invention provides: the new use of compositions of morphine and compounds of Formula II wherein R1 is H or Me, preferably H; R2 is OH, preferably in alpha conformation; R3 is H; or R2 and R3, taken together, are O; R4 is H or Me, preferably Me and preferably in alpha conformation; R5 is H; R6 is H; or R5 and R6, taken together, are O; R7 is H or Me, preferably H; R8=H,OH,OAc,SH,SAc,Cl,Br,F including solvates thereof, pharmaceutically acceptable derivatives thereof, prodrugs thereof, tautomers thereof, isomers thereof, and metabolites thereof.
申请公布号 US6048848(A) 申请公布日期 2000.04.11
申请号 US19980026520 申请日期 1998.02.20
申请人 MONASH UNIVERSITY 发明人 GOODCHILD, COLIN STANLEY;NADESON, RAYMOND
分类号 A01N45/00;A01N47/28;A01N47/34;A61K31/58;A61P29/00;(IPC1-7):A01N45/00 主分类号 A01N45/00
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