发明名称 Hyperthermia and immunotherapy for cancer
摘要 An improved method of inducing whole-body hyperthermia and enhanced anti-tumor immune response through inoculation of a fever virus with nil mortality and subsequent injection of irradiated tumor cells derived from the patient. This therapy will safely reduce the tumor burden by 90-99.9% by physical means (fever), before raising interferon levels to over 250 times baseline. The Activated Lymphokine Killer cells produced by these high interferon levels are capable of killing any cell expressing viral or tumor antigens, even those which had previously escaped immune surveillance. As a final step in the process, a specific class of Cytotoxic T Lymphocytes programmed to destroy the patient's own cancer cells will be produced by repeated inoculation of irradiated cancer cells harvested from the patient. Through a combination of three methods of therapy never previously integrated into a single regimen, it is logical to state that this therapy has a high probability of completely eradicating cancer cells from the patient. In addition, this therapy provides for life-long immunity to the reoccurrence of the disease. It is understood that the examples and embodiments described herein are for illustrative purposes only and that various changes or modifications in light thereof will be suggested to persons skilled in the art and are to be included within the spirit and purview of this application and scope of the appended claims.
申请公布号 US6048686(A) 申请公布日期 2000.04.11
申请号 US19980073322 申请日期 1998.05.05
申请人 RANDY KYLE BROWN 发明人 LYDAY, BRUCE WILLIAM
分类号 A61K35/12;A61K35/76;C12N7/02;(IPC1-7):C12Q1/70;A61K39/193 主分类号 A61K35/12
代理机构 代理人
主权项
地址