A method is provided to determine the ability of a test compound to alter PAK activation of Raf-1 comprising: a) contacting a polypeptide comprising the catalytic domain of a PAK with the test compound in the presence of Raf-1; and b) measuring the extent of activation of Raf-1.
申请公布号
WO0019205(A1)
申请公布日期
2000.04.06
申请号
WO1999US22537
申请日期
1999.09.30
申请人
ADVANCED RESEARCH AND TECHNOLOGY INSTITUTE, INC.;MARSHALL, MARK, S.;DIAZ, HENRY, B.;KING, ALASTAIR, J.;SUN, HUAIYU
