BIOLOGICAL ASSAY COMPOSITIONS CONTAINING NON-INTERFERING, FOAM-INHIBITING AND FOAM-COLLAPSING AGENTS

摘要

There are provided compositions, manufactures and methods for performing biological assays, particularly immunoassays in which the generation and persistence of foam, that can interfere with the assay, is inhibited. Such compositions include, for example silicone-based anti-foaming agents, silicone-glycol emulsions, and polyalkylsiloxane. In a preferred method, the compositions and/or manufactures are used in conjunction with an automated biological assay apparatus which includes a pipetting means which is equipped with a clot detection means.