| 发明名称 |
SUBSTITUTED N-ALIPHATIC-N-AROMATIC TERTIARY-HETEROALKYLAMINES USEFUL FOR INHIBITING CHOLESTERYL ESTER TRANSFER PROTEIN ACTIVITY |
| 摘要 |
The invention relates to substituted N-Aliphatic-N-Aromatic tertiary- Heteroalkylamine compounds useful as inhibitors of cholesteryl ester transfe r protein (CETP; plasma lipid transfer protein-I) and compounds, compositions and methods for treating atherosclerosis, dyslipidemia, and other coronary artery disease.
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| 申请公布号 |
CA2345108(A1) |
申请公布日期 |
2000.04.06 |
| 申请号 |
CA19992345108 |
申请日期 |
1999.09.23 |
| 申请人 |
MONSANTO COMPANY |
发明人 |
PARNAS, BARRY L.;GRAPPERHAUS, MARGARET L.;DURLEY, RICHARD C.;RUEPPEL, MELVIN L.;SIKORSKI, JAMES A.;MISCHKE, DEBORAH A.;REINHARD, EMILY J. |
| 分类号 |
C07D333/20;A61K31/136;A61K31/137;A61K31/138;A61K31/341;A61K31/343;A61K31/351;A61K31/381;A61K31/44;A61K31/4402;A61K31/4406;A61K31/4418;A61K31/443;A61K31/4433;A61K31/4436;A61P3/06;A61P9/00;A61P9/10;A61P43/00;C07C215/08;C07C215/12;C07C217/16;C07C217/20;C07C217/30;C07C217/52;C07C217/58;C07C217/84;C07C217/88;C07C217/90;C07C229/30;C07C229/44;C07D213/65;C07D307/14;C07D307/52;C07D309/04;C07D405/04;C07D409/04;C07D493/08;(IPC1-7):C07C217/52;A61K31/135;C07D309/14;C07C215/16;A61K31/33;C07C215/50;C07C217/54;C07D213/74;C07C215/76;C07C217/82 |
主分类号 |
C07D333/20 |
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