| 发明名称 |
SUBSTITUTED 3-CYANOQUINOLINES AS PROTEIN TYROSINE KINASES INHIBITORS |
| 摘要 |
This invention provides compounds of formula (1), wherein R1, G1, G2, R4, Z, X and n are defined herein, or a pharmaceutically acceptable salt thereof, which are useful as antineoplastic agents and in the treatment of polycystic kidney disease.
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| 申请公布号 |
WO0018740(A1) |
申请公布日期 |
2000.04.06 |
| 申请号 |
WO1999US22056 |
申请日期 |
1999.09.22 |
| 申请人 |
AMERICAN CYANAMID COMPANY |
发明人 |
WISSNER, ALLAN;TSOU, HWEI-RU;BERGER, DAN, MAARTEN;FLOYD, MIDDLETON, BRAWNER, JR.;HAMANN, PHILIP, ROSS;ZHANG, NAN;FROST, PHILIP |
| 分类号 |
A61K31/47;A61K31/4709;A61K31/496;A61K31/5377;A61K31/541;A61K31/553;A61P13/12;A61P35/00;C07D215/54;C07D215/56;C07D401/04;C07D401/12;C07D405/12;C07D409/04;C07D413/12;C07D417/12;C07D491/10;C07D491/113;C07D521/00;(IPC1-7):C07D215/54 |
主分类号 |
A61K31/47 |
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