The present invention is a novel powdered medicament dispenser (10). The powder medicament dispenser includes a novel blade assembly for loading the powder (12) from a reservoir (11) to a dispensing mechanism. In another aspect of the invention, a disposable cartridge (100) is disclosed for use with a medicament dispenser having pressurization and actuation mechanisms. The disposable cartridge (100) affords re-use of the relatively expensive dispenser with different cartridges. The present invention may also be described as a novel method of dispensing a powdered medicament (12). <IMAGE>