| 发明名称 |
Lactam metalloprotease inhibitors. |
| 摘要 |
The present application describes novel lactams and derivatives thereof of formula I: or pharmaceutically acceptable salt forms thereof, wherein rings ring B is a 4-8 membered cyclic amide containing from 0-3 additional heteroatoms selected from N, O, and S, which are useful as metalloprotease inhibitors. |
| 申请公布号 |
ZA9808967(B) |
申请公布日期 |
2000.04.03 |
| 申请号 |
ZA19980008967 |
申请日期 |
1998.10.01 |
| 申请人 |
DUPONT PHARMACEUTICALS COMPANY |
发明人 |
JINGUW DUAN;CARL P. DECICCO;ZELDA R. WASSERMAN;JR. THOMAS P. MADUSKUIE |
| 分类号 |
A61K31/397;A61K31/4015;A61K31/4025;A61K31/403;A61K31/405;A61K31/407;A61K31/41;A61K31/4155;A61K31/4166;A61K31/4178;A61K31/4184;A61K31/4192;A61K31/422;A61K31/4245;A61K31/427;A61K31/433;A61K31/437;A61K31/4427;A61K31/443;A61K31/4433;A61K31/4439;A61K31/4465;A61K31/45;A61K31/451;A61K31/4545;A61K31/4709;A61K31/506;A61K31/5377;A61P1/02;A61P7/00;A61P9/00;A61P17/06;A61P19/02;A61P25/00;A61P27/06;A61P31/18;A61P35/00;A61P37/00;A61P43/00;C07D205/08;C07D207/26;C07D207/273;C07D209/96;C07D211/76;C07D233/32;C07D233/78;C07D401/06;C07D401/10;C07D401/12;C07D401/14;C07D403/06;C07D403/12;C07D403/14;C07D405/06;C07D405/12;C07D405/14;C07D409/06;C07D409/12;C07D413/04;C07D413/10;C07D413/12;C07D413/14;C07D417/10;C07D417/12;C07D417/14;C07D471/04;C07D487/10;C07D491/10 |
主分类号 |
A61K31/397 |
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