| 发明名称 |
MULTILAMELLAR LIPOSOMAL ARACHIDONIC ACID METABOLITE FORMULATIONS |
| 摘要 |
<p>This invention provides a multilamellar liposome containing an arachidonic acid metabolite, two or more lipid-containing bilayers and two or more aqueous compartments containing a release-inhibiting buffer. Preferred arachidonic acid metabolites are the prostaglandins, particularly PGE1. The liposomal formulations can be used to treat animals, particularly humans, for diseases, disorders or conditions which can be ameliorated by prostaglandins, e.g. disorders characterized by cellular activation and ahesion, inflammation and/or toxemia.</p> |
| 申请公布号 |
GR3032006(T3) |
申请公布日期 |
2000.03.31 |
| 申请号 |
GR19990403099T |
申请日期 |
1999.11.30 |
| 申请人 |
THE LIPOSOME CORPORATION |
发明人 |
LENK, ROBERT P.;TOMSHO, MICHELLE L.;SUDDITH, ROBERT L.;KLIMCHAK, ROBERT J.;JANOFF, ANDREW S.;MINCHEY, SHARMA R.;OSTRO, MARC J. |
| 分类号 |
A61K9/127;A61K9/133;A61K31/557;A61K31/5575;A61K47/42;A61P3/08;A61P3/10;A61P7/00;A61P9/08;A61P9/10;A61P11/00;A61P17/00;A61P19/06;A61P29/00;A61P37/00;A61P43/00;(IPC1-7):A61K9/127 |
主分类号 |
A61K9/127 |
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