In-vitro system testing the metabolic interaction between aerobic and anaerobic cell systems for testing metabolism of liver and intestinal cells and anaerobic intestinal micro-flora

摘要

An assembly for measuring the metabolic interaction between aerobic and anaerobic cell systems, is new. A process and assembly registers the metabolic interaction between aerobic and anaerobic cell systems. The assembly consists of a co-culture chamber (2) which is sub-divided by a permeable separation wall, (3) into two chambers (4, 5). The permeable wall (3) surface directed to one wall, (4) has aerobic cell culture components. The other surface of the permeable wall (3) has anaerobic components. The first compartment (4) has an anaerobic gas supply (7a, 7b), while the second compartment (5) has an aerobic gas supply. The movement and migration of substances through the permeable wall is monitored and analyzed in both directions.