发明名称 |
METHOD FOR HIGH SPECIFIC BIOPRODUCTIVITY OF ALPHA, OMEGA-ALKANE DICARBOXYLIC ACIDS USING CANDIDA TROPICALIS |
摘要 |
This invention provides a low-cost method of producing a,w-alkanedicarboxylic acids. Particular bioconversion conditions result in highly efficient conversion of fatty acid, fatty acid ester, or alkane substrates to diacids. Candida tropicalis AR40 or similar yeast strains are grown in a medium containing a carbon source and a nitrogen source at a temperature of 31 DEG C to 38 DEG C, while additional carbon source is continuously added, until maximum cell growth is attained. Within 0-3 hours of this point, substrate is added to the culture to initiate conversion. An a,w-alkanedicarboxylic acid made according to this method is also provided.
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申请公布号 |
WO0017380(A1) |
申请公布日期 |
2000.03.30 |
申请号 |
WO1999US10865 |
申请日期 |
1999.05.17 |
申请人 |
GENERAL ELECTRIC COMPANY |
发明人 |
MOBLEY, DAVID, PAUL;SHANK, GARY, KEITH |
分类号 |
C12P7/44;(IPC1-7):C12P7/44 |
主分类号 |
C12P7/44 |
代理机构 |
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主权项 |
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地址 |
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