QUINOLIZINONES AS INTEGRIN INHIBITORS

摘要

The present invention comprises novel compounds that are effective inhibitors of integrins, particularly alpha IIb beta 3 or alpha v integrins such as alpha v beta 3 and alpha v beta 5. The present invention, according to one embodiment, comprises a compound of formula (I) or formula (II), or a pharmaceutically acceptable salt, solvate, or metabolic precursor thereof. Wherein R1, R2, R3 and R4 are as defined herein.