ENERGY TRANSFER COMPOSITIONS COMPRISING PHYCOBILIPROTEINS

摘要

Energy transfer compositions comprising one or more fluorescent dyes and a fluorescent protein are described, in particular where the fluorescent dye is a sulfonated dye and the fluorescent protein is a phycobiliprotein. The energy transfer compositions of the invention may further comprise additional fluorescent dyes or fluorescent proteins that act as intermediate energy transfer dyes or ultimate emitter dyes. The energy transfer compositions of the invention may also be substituted by chemically reactive functional groups, or covalently bound conjugated substances. The compositions of the invention possess utility as detection reagents and as fluorescent tracers in a wide variety of applications, including biological applications.