发明名称 |
Method for measuring the concentration of polynucleotides |
摘要 |
A method for measuring the concentration of polynucleotide in a sample comprising the steps of: (1) preparing a sample, a Raman scattering active agent capable of bonding to a polynucleotide and a surface-enhanced Raman scattering (SERS) active substrate capable of capturing the agent; (2) mixing the sample, the agent and the substrate to capture the agent which has not been bonded to polynucleotide on the surface of the substrate; (3) irradiating the mixture; and (4) measuring the SERS radiation which is generated by the agent captured on the surface of the substrate.
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申请公布号 |
US6043034(A) |
申请公布日期 |
2000.03.28 |
申请号 |
US19970955251 |
申请日期 |
1997.10.21 |
申请人 |
KYOTO DAIICHI KAGAKU CO., LTD. |
发明人 |
TAKAMA, TOSHIO;WANG, YUNG XIANG;KONO, MASAO;DOU, XIAOMING |
分类号 |
G01N21/65;C12Q1/68;G01N21/64;G01N33/50;G01N33/58;(IPC1-7):C12Q1/68;C07H21/02;C07H21/04;C12N15/00 |
主分类号 |
G01N21/65 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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