发明名称 Gaba beta receptor subtypes gaba beta -R1c and GABA beta-R2 and heterodimers thereof
摘要 The present invention relates to the novel GABAB receptor subtypes GABAB-R1c and GABAB-R2 as well as to a novel, functional GABAB receptor which comprises a heterodimer of GABAB-R1 and GABAB-R2 receptor subunits. The present invention also relates to variant of the receptors, nucleotide sequences encoding the receptors and variants thereof and novel vectors, stable cell lines, antibodies, screening methods, methods of treatment and methods of receptor production.
申请公布号 AU5639799(A) 申请公布日期 2000.03.27
申请号 AU19990056397 申请日期 1999.09.03
申请人 GLAXO GROUP LIMITED 发明人 ASHLEY ANTONY BARNES;ALAN WISE;FIONA HAMILTON MARSHALL;NEIL JAMES FRASER;JULIA HELEN MARGARET WHITE;STEVEN MICHAEL FOORD
分类号 G01N33/50;A61K38/00;A61K39/395;A61K45/00;A61P1/00;A61P1/14;A61P11/00;A61P13/10;A61P25/00;A61P25/08;A61P25/18;A61P25/28;A61P29/00;A61P43/00;C07K14/705;C07K16/28;C12N5/10;C12N15/09;C12N15/12;C12P21/02;C12R1/91;G01N33/15 主分类号 G01N33/50
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