发明名称 SUBSTITUTED PIPERIDINE-EPOXIDE
摘要 PURPOSE: To provide the renine inhibitor using for intercepting to form kyral. CONSTITUTION: After epoxydating the compound of chemical formula (2) or its salt, the compound of chemical formula (1) or its salt is obtained through isolating the solid isomer by voluntary object. In the CHEMICAL FORMULA 1, A is arylene:.R1 is -C¬*R3R4R5, R2 is -O-alkyl, -O-cycloalkyl, -O-alkenyl, -O-aryl, -O-aralkyl, -O-aralkoxyalkyl, -O-alkylsulfonyl, -O-arylsulfonyl, chlorine, brome, or iodine. R3 is hydrogen:R4 is aryl. R5 is alkyl, cycloalkyl, aryl, alkoxyalkyl, or hydroxy alkyl. C is unsymmetrical carbon atom.
申请公布号 KR20000017193(A) 申请公布日期 2000.03.25
申请号 KR19990032562 申请日期 1999.08.09
申请人 F. HOFFMANN-LA ROCHE AG 发明人 GELLER ROLPF;ROLLY BRUNO;SCHMIDT RUDOLPH
分类号 C07D211/52;C07D211/70;C07D211/74;C07D491/04;C07D491/044;(IPC1-7):C07D491/04 主分类号 C07D211/52
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