摘要 |
PURPOSE: To provide the renine inhibitor using for intercepting to form kyral. CONSTITUTION: After epoxydating the compound of chemical formula (2) or its salt, the compound of chemical formula (1) or its salt is obtained through isolating the solid isomer by voluntary object. In the CHEMICAL FORMULA 1, A is arylene:.R1 is -C¬*R3R4R5, R2 is -O-alkyl, -O-cycloalkyl, -O-alkenyl, -O-aryl, -O-aralkyl, -O-aralkoxyalkyl, -O-alkylsulfonyl, -O-arylsulfonyl, chlorine, brome, or iodine. R3 is hydrogen:R4 is aryl. R5 is alkyl, cycloalkyl, aryl, alkoxyalkyl, or hydroxy alkyl. C is unsymmetrical carbon atom. |