COMBINED THERAPY FOR TREATMENT OF INFLAMMATION USING ELASTASE INHIBITOR(S) AND ANTIBACTERIAL AGENT(S)

摘要

A method of treatment is provided to treat inflammation associated with human neutrophil elastase mediated disorders, particularly diseases of respiratory system or oral cavity. The method comprises a combined therapy of administering an elastase inhibitor(s) with an antibacterial agent(s), directed against pathogenic bacteria associated with disease of the respiratory system and oral cavity. A pharmaceutical composition comprising at least one antibacterial agent, and at least one elastase inhibitor is provided, preferably in aerosolized form, as well as a kit containing the respective components in separate packages.