| 摘要 |
<p>The present invention relates to an oral compacted composition comprising entacapone, nitecapone, or a pharmaceutically acceptable salt thereof and a cross-linked cellulose derivative. The composition is premised on the discovery that the cross-linked cellulose derivative increases the release rate of entacapone or nitecapone from an oral compacted composition. Preferably the amount of the cross-linked cellulose derivative in the composition is at least 6 % by weight, preferably from about 8 % to about 16 % weight, especially from about 10 % to about 14 % by weight.</p> |
