On-line parameter estimation and process monitoring, for simulated moving bed chromatography processes comprises taking two continuous measurements to deduce adsorption- and desorption front locations

摘要

Two continuous measurements are made at points of product extraction. Parameters determining physical behavior of the system are determined in real time from the measured data, aided by a mathematical algorithm. Preferred Features: From the measured information, aided by prescribed calculation, concentrations existing within the chromatography columns which cannot be measured, are estimated.