一种新的人神经分化因子

摘要

本发明提供了一种新的人神经分化因子的cDNA序列及其所编码的蛋白质序列。其cDNA序列全长为1990个碱基。其蛋白质序列全长为187个氨基酸。人神经分化因子可能具有促神经细胞分化和抑制神经细胞肿瘤生长的作用。

主权项

1、本发明所提供的人神经生长因子具有如下cDNA序列： 10 20 30 40 50 60gcaaactttc tacagtgaat atatattgtc tttataataa ggaaaaatga ttgaaataaa 70 80 90 100 110 120ttgagaggta taaaacaaaa ctataacaaa ctttcttttg tttattacca tccaacttaa 130 140 150 160 170 180agactgaaaa gtccaagaga tttggaggga tgcaccagta agatccatat tgaccgtaag 190 200 210 220 230 240agaatacaca aggggaatgg tacgctgccc gcacgtaccg cagcccctca ccgtctcagc 250 260 270 280 290 300accactgagg aatcgggctc ctgcacttgg agaccagcct ctgtgaaaca caggtgtagt 310 320 330 340 350 360gagtcatgag atacgctgac aaacgggatg tgaatatcat ggaagctcca aaactcccag 370 380 390 400 410 420taaaggcaaa aagaaaccag ttccccttga cctgtctcca catatcatgg ctctacgtgt 430 440 450 460 470 480gagaagagtt atcactcttt cttcaaagat ttccaggagg gaaggaagga aggaaggaaa 490 500 510 520 530 540gaaggaagga aggaaggaag gaagggaggg agggagggag ggagggaggg aaagaaggag 550 560 570 580 590 600gaagggaaag aaggaggaag ggaacaaaag aaaagggaga aagggaagga gggatggaaa 610 620 630 640 650 660atgtaaccct cataattaaa aaaaaatcaa attgttatta attgccaatt agatcaaagt 670 680 690 700 710 720ttctcacagt tacatttata taggaaaaaa atttaagtag cctaaatgcc caacagcatg 730 740 750 760 770 780agactgacag agaaaatctg ggagactgcc accaactggg gaacggggat accccaagtt 790 800 810 820 830 840tccatactac aagaagaacc agaaatctat gtgatctgtt ccattgagct gttatttctg 850 860 870 880 890 900ggccatgtat gagccagctt taataaaatt aattaaccac tcattcatcg acctccccac 910 920 930 940 950 960cccatccaac atctccgcAT GATGAAACTT CGGCTCACTC CTTGGCGCCT GCCTGATCCT 970 980 990 1000 1010 1020CCAAATCACC ACAGGACTAT TCCTAGCCAT GCACTACTCA CCAGACGCCT CAACCGCCTT 1030 1040 1050 1060 1070 1080TTCATCAATC GCCCACATCA CTCGAGACGT AAATTATGGC TGAATCATCC GCTACCTTCA 1090 1100 1110 1120 1130 1140CGCCAATGGC GCCTCAATAT TCTTTATCTG CCTCTTCCTA CACATCGGGC GAGGCCTATA 1150 1160 1170 1180 1190 1200TTACGGATCA TTTCTCTACT CAGAAACCTG AAACATCGGC ATTATCCTCC TGCTTGCAAC 1210 1220 1230 1240 1250 1260TATAGCAACA GCCTTCATAG GCTATGTCCT CCCGTGAGGC CAAATATCAT TCTGAGGGGC 1270 1280 1290 1300 1310 1320CACAGTAATT ACAAACTTAC TATCCGCCAT CCCATACATT GGGACAGACC TAGTTCAATG 1330 1340 1350 1360 1370 1380AATCTGAGGA GGCTACTCAG TAGACAGTCC CACCCTCACA CGATTCTTTA CCTTTCACTT 1390 1400 1410 1420 1430 1440CATCTTGCCC TTCATTATTA CAGCCCTAGC AGCACTCCAC CTCCTATTCT TGCACGAAAC 1450 1460 1470 1480 1490 1500GGGATCAAAC AACCCCCTAG GAATCACCTC CCATTCCGAT AAaatcacct tccaccctta 1510 1520 1530 1540 1550 1560ctacacaatc aaagacgccc tcggcttact tctcttcctt ctctccttaa tgacattaac 1570 1580 1590 1600 1610 1620actattctca ccagacctcc taggcgaccc agacaattat accctagcca accccttaaa 1630 1640 1650 1660 1670 1680cacccctccc cacatcaagc ccgaatgata tttcctattc gcctacacaa ttctccgatc 1690 1700 1710 1720 1730 1740cgtcccnaac aaactaggag gcgtccttgc cctattacta tccatcctca tcctagcaat 1750 1760 1770 1780 1790 1800aatccccatc ctccatatat ccaaacaaca aagcataata tttcgcccac taagccaatc 1810 1820 1830 1840 1850 1860actttattga ctcctagccg cagacctcct cattctaacc tgaatcggag gacaaccagt 1870 1880 1890 1900 1910 1920aagctaccct tttaccatca ttggacaagt agcatccgta ctatacttca caacaatcct 1930 1940 1950 1960 1970 1980aatcctaata ccaactatct ccctaattga aaacaaaata ctcaaatgag cctaaaaaaa 1990 2000 2010 2020 2030 2040aaaaaaaaaa