发明名称 Retinoyloxy (alkyl-substituted) methyl butyrates useful for the treatment of cancer and other proliferative diseases
摘要 This invention relates to the novel compounds of Formula (I) and pharmaceutical compositions containing same, to methods of treating, preventing or ameliorating cancer and other proliferative diseases in a subject in need of such treatment comprising administering a compound of Formula (I) and pharmaceutically-acceptable salts and prodrugs thereof. The compounds of the invention are also useful in methods of ameliorating wrinkles, inducing wound healing, treating cutaneous ulcers and treating gastrointestinal disorders.
申请公布号 US6040342(A) 申请公布日期 2000.03.21
申请号 US19960674481 申请日期 1996.07.02
申请人 BAR-ILAN UNIVERSITY;KUPAT HOLIM HEALTH INSTITUTION OF THE GENERAL FEDERATION OF LABOR 发明人 REPHAELI, ADA;NUDELMAN, ABRAHAM
分类号 A61K31/225;A61K31/23;A61K31/232;A61K31/44;C07C403/10;C07C403/12;C07D213/30;(IPC1-7):A61K31/225 主分类号 A61K31/225
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