发明名称 |
Retinoyloxy (alkyl-substituted) methyl butyrates useful for the treatment of cancer and other proliferative diseases |
摘要 |
This invention relates to the novel compounds of Formula (I) and pharmaceutical compositions containing same, to methods of treating, preventing or ameliorating cancer and other proliferative diseases in a subject in need of such treatment comprising administering a compound of Formula (I) and pharmaceutically-acceptable salts and prodrugs thereof. The compounds of the invention are also useful in methods of ameliorating wrinkles, inducing wound healing, treating cutaneous ulcers and treating gastrointestinal disorders.
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申请公布号 |
US6040342(A) |
申请公布日期 |
2000.03.21 |
申请号 |
US19960674481 |
申请日期 |
1996.07.02 |
申请人 |
BAR-ILAN UNIVERSITY;KUPAT HOLIM HEALTH INSTITUTION OF THE GENERAL FEDERATION OF LABOR |
发明人 |
REPHAELI, ADA;NUDELMAN, ABRAHAM |
分类号 |
A61K31/225;A61K31/23;A61K31/232;A61K31/44;C07C403/10;C07C403/12;C07D213/30;(IPC1-7):A61K31/225 |
主分类号 |
A61K31/225 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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