Nucleic acids encoding nuclear Dbf2-related (Ndr) kinases

摘要

The current invention describes the identification of a novel widely-expressed human and D. melanogaster serine/threonine protein kinase (designated nuclear, Dbf2-related kinase, or Ndr; previously referred to as Ndr) and the use of this kinase for the identification of agonists and antagonists. The kinase is a nuclear protein and contains a short basic peptide, KRKAETWKRNRR, responsible for the nuclear accumulation.