发明名称 |
UNSATURATED HYDROXIMIC ACID DERIVATIVES AS PARP INHIBITORS |
摘要 |
The object of the invention consists of novel unsaturated hydroximic acid derivatives, the process for their preparation and as active substance such as compounds containing pharmaceutical compositions. The novel compounds possess valuable pharmaceutical effects, so they can be used in the treatment of states connected with energy deficiency of the cell caused by PARP inhibition, in diabetes complications, in oxygen deficient status of the heart and brain, in neurodegenerative diseases, in the treatment of autoimmune and/or viral diseases. In formula (I).
|
申请公布号 |
WO0014054(A1) |
申请公布日期 |
2000.03.16 |
申请号 |
WO1999HU00062 |
申请日期 |
1999.09.02 |
申请人 |
N-GENE KUTATO KFT.;LITERATI NAGY, PETER;SUEMEGI, BALAZS;TAKACS, KALMAN |
发明人 |
LITERATI NAGY, PETER;SUEMEGI, BALAZS;TAKACS, KALMAN |
分类号 |
C07C251/54;A61K31/15;A61K31/40;A61K31/4406;A61K31/4427;A61K31/4453;A61K31/472;A61K31/4725;A61K31/535;A61K31/5375;A61K31/5377;A61P3/00;A61P3/10;A61P7/00;A61P9/00;A61P25/00;A61P31/12;A61P37/02;A61P43/00;C07C249/08;C07C251/58;C07C259/14;C07D207/06;C07D211/14;C07D213/44;C07D213/54;C07D217/04;C07D265/30;C07D295/08;C07D295/088;C07D401/12;(IPC1-7):C07C251/58;A61K31/445;A61K31/155;A61K31/444 |
主分类号 |
C07C251/54 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|