摘要 |
<p>A novel seven-pass transmembrane receptor protein found out in immature dendritic cells; a DNA encoding this protein; a replicable recombinant DNA obtained by integrating the above DNA into a replicable expression vector; microbial or cultured cells transformed by the replicable recombinant DNA as described above; a seven-pass transmembrane receptor protein produced on the cell surface of the above transformant; a method for screening a ligand to the above seven-pass transmembrane receptor protein or a substance preventing the ligand from binding to the seven-pass transmembrane receptor protein; an antibody capable of binding to the seven-pass transmembrane receptor protein; and a method for diagnosing inflammatory diseases such as rheumatism which involves the step of measuring the expression dose of the seven-pass transmembrane receptor protein expressed in human leukocytes.</p> |