摘要 |
<p>A method of analyzing particles for chemical or biological species. Spectral images of the particles are acquired (24, 46). Targets are identified in the images and are classified (52, 80) according to morphology type (78) and spectrum type (76). A descriptor vector (58, 88) is formed and transformed to a vector of mass concentrations of chemical species of interest, or of number concentrations of biological species of interest, using a relationship determined in a calibration procedure. In the calibration procedure, spectral images of calibration samples of known composition are acquired, and empirical morphology types and spectrum types are inferred from the spectral images. Targets are identified in the spectral images and classified according to morphology type and spectrum type. A calibration descriptor vector (58, 88) and a calibration concentration vector (60, 90) is formed. A collection relationship (94) between the calibration descriptor vectors and the calibration concentration vectors is found, either by multivariate analysis or by training a neural network.</p> |