REMOVAL OF EMBEDDING MEDIA FROM BIOLOGICAL SAMPLES AND CELL CONDITIONING ON AUTOMATED STAINING INSTRUMENTS

摘要

The present invention provides an automated for removing or etching embeddin g media by exposing the biological samples for use in histochemical or cytochemical staining procedures without the dependence on organic solvents. The method comprises a biological sample slide in contact with a thermal platform, with or without heat, and with or without a fluid, to facilitate removal or etching of the embedding media from the biological sample. The present invention also provides an automated method for cell conditioning biological samples wherein the cells are predisposed for access by reagent molecules for histochemical and cytochemical staining procedures. The method comprises a biological sample slide in contact with a thermal platform, with or without heat, and with or without a fluid, to facilitate molecular access to cells and cell constituents within the biological sample.