EXOCYCLIC-PHOSPHOETHANOLAMINES

摘要

Disclosed are the use of certain cycloalkyl- and aryl-phosphoethanolamines as anti-inflammatory, anti-arrhythmic and local anesthetic agents. These therapeutically active cycloalkyl- and aryl-phosphoethanolamines are of the general Formula (I): R—O—PEA, wherein R is an unsubstituted or a substituted C5-7 cycloalkyl or an unsubstituted or substituted phenyl in which each substituent is hydrogen or an unsubstituted or substituted straight or branched C1-4 alkyl or C2-4 alkenyl, said substitution being one or more of C1-4 alkoxy, halo or cyano; and -O—PEA represents a phosphoethanolamine substituent. Also disclosed are intermediates for producing Formula (I) compounds.