NOCATHIACIN ANTIBIOTIC DERIVATIVES PREPARED BY MICROBIAL BIOTRANSFORMATION

摘要

Fermentation of Actinoplanes sp. ATCC 53771 or Amycolata autotrophica ATCC 35204 in the presence of nocathiacin yields a new compound nocathiacin 6-deoxyglycoside which has broad spectrum antibiotic activity against Gram-positive bacteria and has in vivo efficacy in animals.