| 发明名称 |
VIRAL NUCLEOTIDE SEQUENCES |
| 摘要 |
<p>A vaccine effective against Marek's disease virus (MDV) comprises (a) an MDV attenuated by virtue of being TK<-> or (b) a host expressing an MDV antigen, namely the respective MDV homologues of the HSV gB, gC, gD or gH glycoproteins (or antigenic parts thereof) or the respective MDV homologues of the HSV-1 immediate early genes IE-68 or IE-175. The host may be a herpes virus of turkeys (HVT), more particularly HVT in which the MDV antigen is inserted in the HVT homologue of the HSV gC gene, the ribonucleotide reductase (large subunit) gene or the thymidine kinase (TK) gene.</p> |
| 申请公布号 |
EP0434721(B1) |
申请公布日期 |
2000.03.15 |
| 申请号 |
EP19890910146 |
申请日期 |
1989.09.13 |
| 申请人 |
MERIAL |
发明人 |
GRIFFIN, ANNETTE, MARY;ROSS, LOUIS, J.N.;SCOTT, SIMON, DAVID;BINNS, MATTHEW, M. |
| 分类号 |
A01K67/027;A61K31/00;A61K35/76;A61K38/00;A61K39/00;A61K39/12;A61K39/215;A61K39/245;A61K39/255;A61K39/265;A61K39/275;A61K39/295;A61K48/00;A61P31/00;A61P31/12;A61P31/20;A61P31/22;A61P37/04;C07K14/00;C07K14/005;C07K14/03;C07K14/035;C07K14/055;C07K14/195;C12N;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N7/00;C12N7/01;C12N7/04;C12N9/02;C12N9/12;C12N15/00;C12N15/09;C12N15/33;C12N15/38;C12N15/45;C12N15/86;C12N15/869;C12P21/02;C12R1/91;C12R1/92;(IPC1-7):C12N15/38 |
主分类号 |
A01K67/027 |
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