发明名称 Enzyme-catalyzed racemic cleavage of primary amines
摘要 The present invention relates to a process for resolving racemates of alkoxy-substituted primary amines by reacting with an ester in the presence of a lipase and subsequently separating the optically active amide which is formed from the unreacted optically active amine. This is followed where appropriate by hydrolysis of the optically active amide, separation of the optically active amine produced thereby from the acid from which the ester is derived, racemization and recycling of the unwanted enantiomer of the amine, and esterification and recycling of the acid.
申请公布号 AU5516499(A) 申请公布日期 2000.03.14
申请号 AU19990055164 申请日期 1999.08.13
申请人 BASF AKTIENGESELLSCHAFT 发明人 CHRISTOPH NUBLING;KLAUS DITRICH;CHRISTIAN DULLY
分类号 C07C213/08;C07C217/08;C12P13/02;C12P41/00 主分类号 C07C213/08
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