| 摘要 |
PROBLEM TO BE SOLVED: To detect an infection due to pseudomonas aeruginosa by providing the outer membrane protein F of pseudomonas aeruginosa with an amino acid sequence, DNA to code for the outer membrane protein F, antibodies to DNA, and a diagnosis assistant and compositions containing them. SOLUTION: Compositions are based on the complete specificity of genes to OMPF from P.aeruginosa, serotype 6, and ATCC33354. A DNA sequence and an amino acid sequence derived from this are shown in Fig. The amino acid sequence is arranged below the one-letter code below associated triplets, and signal peptides are emphasized by italic letters. The protein of an outer membrane is obtained from a Pyrenomycete stock, and OMPF is concentrated from it by HPLC. An initial sequence is that of an amino terminal and is that of a protein piece obtained by cutting by trypsin. These oligopeptides and DNA sequence to code for are derived to synthesize oligodexynucleotide.
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