发明名称 |
Method of screening for compounds that modulate the activity of a molecular target |
摘要 |
The present invention provides a method for generating and isolating cell lines that functionally express molecular targets for drug discovery without utilizing information from the nucleic acid or amino acid sequence of the target protein. This procedure for the first time allows one to develop fast, high throughput screens for evaluation of test compounds that may modulate molecular targets whose specific nucleic acid or amino acid sequences are unavailable. |
申请公布号 |
AU5485499(A) |
申请公布日期 |
2000.03.14 |
申请号 |
AU19990054854 |
申请日期 |
1999.08.12 |
申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
C. DAVID WEAVER;TODD A. VERDOORN;GORDON WILLIAM ROBINSON |
分类号 |
C07K14/47;C12N15/10;C12Q1/68 |
主分类号 |
C07K14/47 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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