STRUCTURAL PHOSPHOPROTEIN (PP 150) OF HUMAN CYTOMEGALOVIRUS, AND THE PREPARATION THEREOF

摘要

The phosphorylated structural protein of molecular weight about 150 kd (pp 150) of human cytomegalovirus (HCMV) is highly immunogenic and is reliably recognised by human antisera. This protein can, after assignment and sequencing of the gene, be prepared, in whole or in immunogenic sections, by gene manipulation. Proteins of this type are suitable as reagents, for example in an ELISA, and as constituents of vaccines.