| 摘要 |
The use of a bioreductive conjugate comprised of a non-cytoxic bioreductive moiety having linked thereto at least one therapeutic agent, and salts thereof, is disclosed for the healing of wounds and the treatment of fibrotic disorders, ulcerative colitis, inflammatory bowel disease, epilepsy, cardiovascular reperfusion injury, cerebral reperfusion injury, hypertensions, cystic fibrosis, psoriasis, para-psoriasis, peptic ulcers, gastric ulcers, duodenal ulcers, diabetic ulcers dementia, oncology, Aids, rheumatoid arthritis, diabetes, and ischemia. Various specific conjugates for treating these conditions are also disclosed. |
