COMBINATION OF RADIOTHERAPY AND ANTI-ANGIOGENIC FACTORS
摘要
The present invention relates generally to the fields of angiogenesis and cancer therapy. More particularly, it concerns the use of anti-angiogenic factors in cancer therapy. The present invention demonstrates that angiostatin or endostatin can sensitize a cell to radiation therapy. Methods and compositions for inhibiting growth, sensitizing a cell to radiotherapy and treating cancer growth by first inhibiting angiogenesis and then employing radiotherapy are described.
申请公布号
WO9965515(A3)
申请公布日期
2000.03.09
申请号
WO1999US13567
申请日期
1999.06.15
申请人
ARCH DEVELOPMENT CORPORATION;BETH ISRAEL DEACONESS MEDICAL CENTER, INC.;DANA-FARBER CANCER INSTITUTE, INC.;WEICHSELBAUM, RALPH, R.;SUKHATME, VIKAS, P.;KUFE, DONALD, W.
发明人
WEICHSELBAUM, RALPH, R.;SUKHATME, VIKAS, P.;KUFE, DONALD, W.
