发明名称 2-ARYL-4-(1-[4-HETEROARYL]PIPERAZIN-1-YL) METHYLIMIDAZOLES: DOPAMINE D4 RECEPTOR SUBTYPE LIGANDS
摘要 <p>Disclosed are compounds of formula: (I) or the pharmaceutically acceptable acid addition salts thereof wherein Ra represents (II) where X, Y and Z are the same or different and represent CH or nitrogen; R1, R2, R3 and R4 independently represent organic or inorganic groups: and R5 is hydrogen, C1-C6 alkyl or halogen, which compounds are useful for the treatment and/or prevention of neuropsychological disorders including, but not limited to, schizophrenia, mania, dementia, depression, anxiety, compulsive behaviour, substance abuse, Parkinson-like motor disorders and motion disorders related to the use of neuroleptic agents.</p>
申请公布号 WO2000012500(A2) 申请公布日期 2000.03.09
申请号 US1999020176 申请日期 1999.09.02
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