Purified BMP-15-related proteins and processes for producing them are disclosed. DNA molecules encoding the BMP-15-related proteins are also disclosed. The proteins may be used in the treatment of bone and cartilage and/or other connective tissue defects and in wound healing and related tissue repair.
申请公布号
US6034229(A)
申请公布日期
2000.03.07
申请号
US19970982987
申请日期
1997.12.02
申请人
GENETICS INSTITUTE, INC.;VANDERBILT UNIVERSITY
发明人
CELESTE, ANTHONY J.;DUBE, JENNIFER L.;LYONS, KAREN M.;HOGAN, BRIGID