ACTIVE SPECIFIC IMMUNOTHERAPY OF ADENOCARCINOMAS PRODUCING IMMUNOSUPPRESSIVE MUCINS

摘要

A synergistic composition is provided herein for inhibiting the growth of an adenocarcinoma tumour. The tumour is associated with a mucin having immunosuppressive activity. The composition comprises: an immune-response-potentiating amount of cyclophosphamide, and an immuno-genically-effective amount of a carbohydrate epitope-bearing antigen. Such antigen is immunologically cross-reactive with a mucin having immunosuppressive activity associated with the tumour.