发明名称 |
CARBONYL-STRESS IMPROVING AGENT AND PERITONEAL DIALYSATE |
摘要 |
Carbonyl compounds generated and accumulated in the peritoneal dialysate can be inactivated or eliminated by a carbonyl compound-trapping agent such as aminoguanidine. Carbonyl compounds generated during sterilization and storage of the peritoneal dialysate can be eliminated by pre-contacting with the trapping agent. Further, it is possible to eliminate carbonyl compounds transferred from the blood to the peritoneal cavity of the patient during peritoneal dialysis treatment, by adding the trapping agent to the peritoneal dialysate or by circulating the fluid through a carbonyl compound-trapping cartridge. Intraperitoneal protein modification by carbonyl compounds is inhibited by the present invention, thereby sufficiently reducing peritoneal disorders associated with peritoneal dialysis treatment.
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申请公布号 |
CA2664159(A1) |
申请公布日期 |
2000.03.02 |
申请号 |
CA19992664159 |
申请日期 |
1999.08.23 |
申请人 |
TOKAI UNIVERSITY EDUCATIONAL SYSTEM;KUROKAWA, KIYOSHI;MIYATA, TOSHIO |
发明人 |
KUROKAWA, KIYOSHI;MIYATA, TOSHIO |
分类号 |
A61M1/28;A61K31/155;A61K31/44;A61K47/30 |
主分类号 |
A61M1/28 |
代理机构 |
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